N-acetylcysteine addition after vitrification improves oocyte mitochondrial polarization status and the quality of embryos derived from vitrified murine oocytes

BACKGROUND: Vitrification is the safest method to cryopreserve oocytes, however the process alters mitochondrial function resulting from increased reactive oxygen species (ROS) production. Our aim was to alleviate ROS stress in vitrified mice oocytes using N-acetylcysteine (NAC at 1 mM), to improve...

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Detalles Bibliográficos
Autores principales: Matilla, Elvira, Martín-Cano, Francisco Eduardo, González-Fernández, Lauro, Sánchez-Margallo, Francisco Miguel, Álvarez, Ignacio Santiago, Macías-García, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337864/
https://www.ncbi.nlm.nih.gov/pubmed/30654800
http://dx.doi.org/10.1186/s12917-018-1743-2

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