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Predicted antiviral activity of tenofovir versus abacavir in combination with a cytosine analogue and the integrase inhibitor dolutegravir in HIV-1-infected South African patients initiating or failing first-line ART
OBJECTIVES: The WHO recently recommended the use of a new first-line ART containing dolutegravir. We investigated the efficacy of NRTI backbones (tenofovir or abacavir with a cytosine analogue) in low- and middle-income countries where there is significant prior exposure to antiretrovirals and drug...
Autores principales: | Derache, Anne, Iwuji, Collins C, Danaviah, Siva, Giandhari, Jennifer, Marcelin, Anne-Geneviève, Calvez, Vincent, de Oliveira, Tulio, Dabis, François, Pillay, Deenan, Gupta, Ravindra K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337894/ https://www.ncbi.nlm.nih.gov/pubmed/30380053 http://dx.doi.org/10.1093/jac/dky428 |
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