Contemporary grading of prostate cancer: 2017 update for pathologists and clinicians

The Gleason grading system for prostate cancer (PCa) was developed in the 1960s by DF Gleason. Due to changes in PCa detection and treatment, the application of the Gleason grading system has changed considerably in pathology routine practice. Two consensus conferences were held in 2005 and in 2014...

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Detalles Bibliográficos
Autores principales: Gasparrini, Silvia, Cimadamore, Alessia, Scarpelli, Marina, Massari, Francesco, Doria, Andrea, Mazzucchelli, Roberta, Cheng, Liang, Lopez-Beltran, Antonio, Montironi, Rodolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337944/
https://www.ncbi.nlm.nih.gov/pubmed/28782737
http://dx.doi.org/10.4103/aja.aja_24_17
Descripción
Sumario:The Gleason grading system for prostate cancer (PCa) was developed in the 1960s by DF Gleason. Due to changes in PCa detection and treatment, the application of the Gleason grading system has changed considerably in pathology routine practice. Two consensus conferences were held in 2005 and in 2014 to update PCa Gleason grading. This review provides a summary of the changes in the grading of PCa from the original Gleason grading system to the prognostic grade grouping, as well as a discussion of the clinical significance of the percentage of Gleason patterns 4 and 5.

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