Contemporary grading of prostate cancer: 2017 update for pathologists and clinicians

The Gleason grading system for prostate cancer (PCa) was developed in the 1960s by DF Gleason. Due to changes in PCa detection and treatment, the application of the Gleason grading system has changed considerably in pathology routine practice. Two consensus conferences were held in 2005 and in 2014...

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Autores principales: Gasparrini, Silvia, Cimadamore, Alessia, Scarpelli, Marina, Massari, Francesco, Doria, Andrea, Mazzucchelli, Roberta, Cheng, Liang, Lopez-Beltran, Antonio, Montironi, Rodolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337944/
https://www.ncbi.nlm.nih.gov/pubmed/28782737
http://dx.doi.org/10.4103/aja.aja_24_17
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author Gasparrini, Silvia
Cimadamore, Alessia
Scarpelli, Marina
Massari, Francesco
Doria, Andrea
Mazzucchelli, Roberta
Cheng, Liang
Lopez-Beltran, Antonio
Montironi, Rodolfo
author_facet Gasparrini, Silvia
Cimadamore, Alessia
Scarpelli, Marina
Massari, Francesco
Doria, Andrea
Mazzucchelli, Roberta
Cheng, Liang
Lopez-Beltran, Antonio
Montironi, Rodolfo
author_sort Gasparrini, Silvia
collection PubMed
description The Gleason grading system for prostate cancer (PCa) was developed in the 1960s by DF Gleason. Due to changes in PCa detection and treatment, the application of the Gleason grading system has changed considerably in pathology routine practice. Two consensus conferences were held in 2005 and in 2014 to update PCa Gleason grading. This review provides a summary of the changes in the grading of PCa from the original Gleason grading system to the prognostic grade grouping, as well as a discussion of the clinical significance of the percentage of Gleason patterns 4 and 5.
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spelling pubmed-63379442019-02-14 Contemporary grading of prostate cancer: 2017 update for pathologists and clinicians Gasparrini, Silvia Cimadamore, Alessia Scarpelli, Marina Massari, Francesco Doria, Andrea Mazzucchelli, Roberta Cheng, Liang Lopez-Beltran, Antonio Montironi, Rodolfo Asian J Androl Invited Review The Gleason grading system for prostate cancer (PCa) was developed in the 1960s by DF Gleason. Due to changes in PCa detection and treatment, the application of the Gleason grading system has changed considerably in pathology routine practice. Two consensus conferences were held in 2005 and in 2014 to update PCa Gleason grading. This review provides a summary of the changes in the grading of PCa from the original Gleason grading system to the prognostic grade grouping, as well as a discussion of the clinical significance of the percentage of Gleason patterns 4 and 5. Medknow Publications & Media Pvt Ltd 2019 2017-08-04 /pmc/articles/PMC6337944/ /pubmed/28782737 http://dx.doi.org/10.4103/aja.aja_24_17 Text en Copyright: © The Author(s)(2017) http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Invited Review
Gasparrini, Silvia
Cimadamore, Alessia
Scarpelli, Marina
Massari, Francesco
Doria, Andrea
Mazzucchelli, Roberta
Cheng, Liang
Lopez-Beltran, Antonio
Montironi, Rodolfo
Contemporary grading of prostate cancer: 2017 update for pathologists and clinicians
title Contemporary grading of prostate cancer: 2017 update for pathologists and clinicians
title_full Contemporary grading of prostate cancer: 2017 update for pathologists and clinicians
title_fullStr Contemporary grading of prostate cancer: 2017 update for pathologists and clinicians
title_full_unstemmed Contemporary grading of prostate cancer: 2017 update for pathologists and clinicians
title_short Contemporary grading of prostate cancer: 2017 update for pathologists and clinicians
title_sort contemporary grading of prostate cancer: 2017 update for pathologists and clinicians
topic Invited Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337944/
https://www.ncbi.nlm.nih.gov/pubmed/28782737
http://dx.doi.org/10.4103/aja.aja_24_17
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