G protein-coupled receptor kinase 2 inhibition improves erectile function through amelioration of endothelial dysfunction and oxidative stress in a rat model of type 2 diabetes

Type 2 diabetes mellitus (T2DM) is a common cause of erectile dysfunction (ED). It has been demonstrated that G protein-coupled receptor kinase 2 (GRK2) overexpression contributes to diabetic endothelial dysfunction and oxidative stress, which also underlies ED in T2DM. We hypothesized that GRK2 ove...

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Detalles Bibliográficos
Autores principales: Wan, Zhi-Hua, Zhang, Yuan-Jie, Chen, Lin, Guo, Yong-Lian, Li, Guo-Hao, Wu, Ding, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337949/
https://www.ncbi.nlm.nih.gov/pubmed/30226217
http://dx.doi.org/10.4103/aja.aja_69_18

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