Royal Jelly Alleviates Cognitive Deficits and β-Amyloid Accumulation in APP/PS1 Mouse Model Via Activation of the cAMP/PKA/CREB/BDNF Pathway and Inhibition of Neuronal Apoptosis

Alzheimer’s disease (AD) is characterized clinically by progressive cognitive decline and pathologically by the accumulation of amyloid-β (Aβ) in the brain. Royal jelly (RJ), a secretion of honeybee hypopharyngeal and mandibular glands, has previously been shown to have anti-aging and neuromodulator...

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Detalles Bibliográficos
Autores principales: You, Mengmeng, Pan, Yongming, Liu, Yichen, Chen, Yifan, Wu, Yuqi, Si, Juanjuan, Wang, Kai, Hu, Fuliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338040/
https://www.ncbi.nlm.nih.gov/pubmed/30687079
http://dx.doi.org/10.3389/fnagi.2018.00428

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