Cargando…
Th1 cytokines sensitize HER-expressing breast cancer cells to lapatinib
The HER family of receptor tyrosine kinases has been linked to deregulation of growth and proliferation for multiple types of cancer. Members have therefore become thefocus of many drug and immune-based therapy innovations. The targeted anti-cancer agent, lapatinib, is a small molecule inhibitor tha...
Autores principales: | Showalter, Loral E., Oechsle, Crystal, Ghimirey, Nirmala, Steele, Chase, Czerniecki, Brian J., Koski, Gary K. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338365/ https://www.ncbi.nlm.nih.gov/pubmed/30657766 http://dx.doi.org/10.1371/journal.pone.0210209 |
Ejemplares similares
-
Sunitinib Combined with Th1 Cytokines Potentiates Apoptosis in Human Breast Cancer Cells and Suppresses Tumor Growth in a Murine Model of HER-2(pos) Breast Cancer
por: Ghimirey, Nirmala, et al.
Publicado: (2021) -
Statin Drugs Plus Th1 Cytokines Potentiate Apoptosis and Ras Delocalization in Human Breast Cancer Lines and Combine with Dendritic Cell-Based Immunotherapy to Suppress Tumor Growth in a Mouse Model of HER-2(pos) Disease
por: Oechsle, Crystal M., et al.
Publicado: (2020) -
Th1 cytokines in conjunction with pharmacological Akt inhibition potentiate apoptosis of breast cancer cells in vitro and suppress tumor growth in vivo
por: Showalter, Loral, et al.
Publicado: (2020) -
Murine Dendritic Cells Grown in Serum-Free Culture Show Potent Therapeutic Activity when Loaded with Novel Th Epitopes in an Orthotopic Model of HER2(pos) Breast Cancer
por: Showalter, Loral E., et al.
Publicado: (2021) -
T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells
por: Namjoshi, Prachi, et al.
Publicado: (2019)