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Synergy between RecBCD subunits is essential for efficient DNA unwinding

The subunits of the bacterial RecBCD act in coordination, rapidly and processively unwinding DNA at the site of a double strand break. RecBCD is able to displace DNA-binding proteins, suggesting that it generates high forces, but the specific role of each subunit in the force generation is unclear....

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Detalles Bibliográficos
Autores principales: Zananiri, Rani, Malik, Omri, Rudnizky, Sergei, Gaydar, Vera, Kreiserman, Roman, Henn, Arnon, Kaplan, Ariel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338465/
https://www.ncbi.nlm.nih.gov/pubmed/30601118
http://dx.doi.org/10.7554/eLife.40836