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Overexpression of miR-489 derails mammary hierarchy structure and inhibits HER2/neu-induced tumorigenesis
Although it has been demonstrated that transformed progenitor cell population can contribute to tumor initiation, factors contributing to this malignant transformation are poorly known. Using in vitro and xenograft based models, previous studies demonstrated that miR-489 acts as a tumor suppressor m...
Autores principales: | Patel, Y, Soni, M, Awagulerwitsch, A, Kern, MJ, Liu, S, Shah, N, Singh, UP, Chen, H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338493/ https://www.ncbi.nlm.nih.gov/pubmed/30104710 http://dx.doi.org/10.1038/s41388-018-0439-1 |
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