Stat3 is indispensable for damage-induced crypt regeneration but not for Wnt-driven intestinal tumorigenesis

Signal transducer and activator of transcription 3 (Stat3) has been shown to play a role in intestinal regeneration and colitis-associated colon carcinogenesis. However, the role of Stat3 in the Wnt-driven sporadic intestinal tumorigenesis remains poorly understood. We examined the roles of Stat3 in...

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Detalles Bibliográficos
Autores principales: Oshima, Hiroko, Kok, Sau-Yee, Nakayama, Mizuho, Murakami, Kazuhiro, Voon, Dominic Chih-Cheng, Kimura, Takashi, Oshima, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338624/
https://www.ncbi.nlm.nih.gov/pubmed/30156908
http://dx.doi.org/10.1096/fj.201801176R

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