Genes controlling the activation of natural killer lymphocytes are epigenetically remodeled in intestinal cells from germ-free mice

Remodeling of the gut microbiota is implicated in various metabolic and inflammatory diseases of the gastrointestinal tract. We hypothesized that the gut microbiota affects the DNA methylation profile of intestinal epithelial cells (IECs) which could, in turn, alter intestinal function. In this stud...

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Detalles Bibliográficos
Autores principales: Poupeau, Audrey, Garde, Christian, Sulek, Karolina, Citirikkaya, Kiymet, Treebak, Jonas T., Arumugam, Manimozhiyan, Simar, David, Olofsson, Louise E., Bäckhed, Fredrik, Barrès, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338647/
https://www.ncbi.nlm.nih.gov/pubmed/30303739
http://dx.doi.org/10.1096/fj.201800787R

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