Repurposing simvastatin as a therapy for preterm labor: evidence from preclinical models

Preterm birth (PTB), the leading cause of neonatal morbidity and mortality, urgently requires novel therapeutic agents. Spontaneous PTB, resulting from preterm labor, is commonly caused by intrauterine infection/inflammation. Statins are well-established, cholesterol-lowering drugs that can reduce i...

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Detalles Bibliográficos
Autores principales: Boyle, Ashley K., Rinaldi, Sara F., Rossi, Adriano G., Saunders, Philippa T. K., Norman, Jane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338657/
https://www.ncbi.nlm.nih.gov/pubmed/30312114
http://dx.doi.org/10.1096/fj.201801104R

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