Parent-of-origin effects on quantitative phenotypes in a large Hutterite pedigree

The impact of the parental origin of associated alleles in GWAS has been largely ignored. Yet sequence variants could affect traits differently depending on whether they are inherited from the mother or the father, as in imprinted regions, where identical inherited DNA sequences can have different e...

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Detalles Bibliográficos
Autores principales: Mozaffari, Sahar V., DeCara, Jeanne M., Shah, Sanjiv J., Sidore, Carlo, Fiorillo, Edoardo, Cucca, Francesco, Lang, Roberto M., Nicolae, Dan L., Ober, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338666/
https://www.ncbi.nlm.nih.gov/pubmed/30675526
http://dx.doi.org/10.1038/s42003-018-0267-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338666/
https://www.ncbi.nlm.nih.gov/pubmed/30675526
http://dx.doi.org/10.1038/s42003-018-0267-4

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