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Parent-of-origin effects on quantitative phenotypes in a large Hutterite pedigree
The impact of the parental origin of associated alleles in GWAS has been largely ignored. Yet sequence variants could affect traits differently depending on whether they are inherited from the mother or the father, as in imprinted regions, where identical inherited DNA sequences can have different e...
Autores principales: | Mozaffari, Sahar V., DeCara, Jeanne M., Shah, Sanjiv J., Sidore, Carlo, Fiorillo, Edoardo, Cucca, Francesco, Lang, Roberto M., Nicolae, Dan L., Ober, Carole |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338666/ https://www.ncbi.nlm.nih.gov/pubmed/30675526 http://dx.doi.org/10.1038/s42003-018-0267-4 |
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