The intact postsynaptic protein neurogranin is reduced in brain tissue from patients with familial and sporadic Alzheimer’s disease

Synaptic degeneration and neuronal loss are early events in Alzheimer’s disease (AD), occurring long before symptom onset, thus making synaptic biomarkers relevant for enabling early diagnosis. The postsynaptic protein neurogranin (Ng) is a cerebrospinal fluid (CSF) biomarker for AD, also in the pro...

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Detalles Bibliográficos
Autores principales: Kvartsberg, Hlin, Lashley, Tammaryn, Murray, Christina E., Brinkmalm, Gunnar, Cullen, Nicholas C., Höglund, Kina, Zetterberg, Henrik, Blennow, Kaj, Portelius, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338696/
https://www.ncbi.nlm.nih.gov/pubmed/30244311
http://dx.doi.org/10.1007/s00401-018-1910-3

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