Structure and evolution of double minutes in diagnosis and relapse brain tumors

Double minute chromosomes are extrachromosomal circular DNA fragments frequently found in brain tumors. To understand their evolution, we characterized the double minutes in paired diagnosis and relapse tumors from a pediatric high-grade glioma and four adult glioblastoma patients. We determined the...

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Detalles Bibliográficos
Autores principales: Xu, Ke, Ding, Liang, Chang, Ti-Cheng, Shao, Ying, Chiang, Jason, Mulder, Heather, Wang, Shuoguo, Shaw, Tim I., Wen, Ji, Hover, Laura, McLeod, Clay, Wang, Yong-Dong, Easton, John, Rusch, Michael, Dalton, James, Downing, James R., Ellison, David W., Zhang, Jinghui, Baker, Suzanne J., Wu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338707/
https://www.ncbi.nlm.nih.gov/pubmed/30267146
http://dx.doi.org/10.1007/s00401-018-1912-1

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