Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease

Human gut microbiota senses its environment and responds by releasing metabolites, some of which are key regulators of human health and disease. In this study, we characterize gut-associated bacteria in their ability to decarboxylate levodopa to dopamine via tyrosine decarboxylases. Bacterial tyrosi...

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Detalles Bibliográficos
Autores principales: van Kessel, Sebastiaan P., Frye, Alexandra K., El-Gendy, Ahmed O., Castejon, Maria, Keshavarzian, Ali, van Dijk, Gertjan, El Aidy, Sahar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338741/
https://www.ncbi.nlm.nih.gov/pubmed/30659181
http://dx.doi.org/10.1038/s41467-019-08294-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338741/
https://www.ncbi.nlm.nih.gov/pubmed/30659181
http://dx.doi.org/10.1038/s41467-019-08294-y

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