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Gut bacterial tyrosine decarboxylases restrict levels of levodopa in the treatment of Parkinson’s disease
Human gut microbiota senses its environment and responds by releasing metabolites, some of which are key regulators of human health and disease. In this study, we characterize gut-associated bacteria in their ability to decarboxylate levodopa to dopamine via tyrosine decarboxylases. Bacterial tyrosi...
Autores principales: | van Kessel, Sebastiaan P., Frye, Alexandra K., El-Gendy, Ahmed O., Castejon, Maria, Keshavarzian, Ali, van Dijk, Gertjan, El Aidy, Sahar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338741/ https://www.ncbi.nlm.nih.gov/pubmed/30659181 http://dx.doi.org/10.1038/s41467-019-08294-y |
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