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Claudin-3-deficient C57BL/6J mice display intact brain barriers

The tight junction protein claudin-3 has been identified as a transcriptional target of the Wnt/β-catenin signaling pathway regulating blood-brain barrier (BBB) maturation. In neurological disorders loss of claudin-3 immunostaining is observed at the compromised BBB and blood-cerebrospinal fluid bar...

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Detalles Bibliográficos
Autores principales:	Castro Dias, Mariana, Coisne, Caroline, Lazarevic, Ivana, Baden, Pascale, Hata, Masaki, Iwamoto, Noriko, Francisco, David Miguel Ferreira, Vanlandewijck, Michael, He, Liqun, Baier, Felix A., Stroka, Deborah, Bruggmann, Rémy, Lyck, Ruth, Enzmann, Gaby, Deutsch, Urban, Betsholtz, Christer, Furuse, Mikio, Tsukita, Shoichiro, Engelhardt, Britta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338742/ https://www.ncbi.nlm.nih.gov/pubmed/30659216 http://dx.doi.org/10.1038/s41598-018-36731-3

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