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Disulfiram and BKM120 in Combination with Chemotherapy Impede Tumor Progression and Delay Tumor Recurrence in Tumor Initiating Cell-Rich TNBC

Tumor initiating cells (TIC) have been suggested as a mechanism for driving chemoresistance and tumor recurrence in human cancers including triple negative breast cancer (TNBC). Significant progress has been made in targeting TICs. However, methods for simultaneously targeting heterogeneous TIC popu...

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Detalles Bibliográficos
Autores principales: Wu, Ling, Meng, Fanyan, Dong, Lun, Block, C. James, Mitchell, Allison V., Wu, Jason, Jang, Hyejeong, Chen, Wei, Polin, Lisa, Yang, Qifeng, Dou, Q. Ping, Wu, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338744/
https://www.ncbi.nlm.nih.gov/pubmed/30659204
http://dx.doi.org/10.1038/s41598-018-35619-6