Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

Large studies use genotype data to discover genetic contributions to complex traits and infer relationships between those traits. Co-incident geographical variation in genotypes and health traits can bias these analyses. Here we show that single genetic variants and genetic scores composed of multip...

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Detalles Bibliográficos
Autores principales: Haworth, Simon, Mitchell, Ruth, Corbin, Laura, Wade, Kaitlin H., Dudding, Tom, Budu-Aggrey, Ashley, Carslake, David, Hemani, Gibran, Paternoster, Lavinia, Smith, George Davey, Davies, Neil, Lawson, Daniel J., J. Timpson, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338768/
https://www.ncbi.nlm.nih.gov/pubmed/30659178
http://dx.doi.org/10.1038/s41467-018-08219-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338768/
https://www.ncbi.nlm.nih.gov/pubmed/30659178
http://dx.doi.org/10.1038/s41467-018-08219-1

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