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Epstein-Barr Virus Latent Membrane Protein-1 Induces the Expression of SUMO-1 and SUMO-2/3 in LMP1-positive Lymphomas and Cells
Epstein-Barr Virus latent membrane protein-1 (LMP1) interacts with the SUMO-conjugating enzyme Ubc9, which induces protein sumoylation and may contribute to LMP1-mediated oncogenesis. After analyzing human lymphoma tissues and EBV-positive cell lines, we now document a strong correlation between LMP...
Autores principales: | Salahuddin, Sadia, Fath, Emma K., Biel, Natalie, Ray, Ashley, Moss, C. Randall, Patel, Akash, Patel, Sheetal, Hilding, Leslie, Varn, Matthew, Ross, Tabithia, Cramblet, Wyatt T., Lowrey, Angela, Pagano, Joseph S., Shackelford, Julia, Bentz, Gretchen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338769/ https://www.ncbi.nlm.nih.gov/pubmed/30659232 http://dx.doi.org/10.1038/s41598-018-36312-4 |
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