Noninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions

Spatiotemporal control of gene expression or labeling is a valuable strategy for identifying functions of genes within complex neural circuits. Here, we develop a highly light-sensitive and efficient photoactivatable Flp recombinase (PA-Flp) that is suitable for genetic manipulation in vivo. The hig...

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Detalles Bibliográficos
Autores principales: Jung, Hyunjin, Kim, Seong-Wook, Kim, Minsoo, Hong, Jongryul, Yu, Daseuli, Kim, Ji Hye, Lee, Yunju, Kim, Sungsoo, Woo, Doyeon, Shin, Hee-Sup, Park, Byung Ouk, Heo, Won Do
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338782/
https://www.ncbi.nlm.nih.gov/pubmed/30659191
http://dx.doi.org/10.1038/s41467-018-08282-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338782/
https://www.ncbi.nlm.nih.gov/pubmed/30659191
http://dx.doi.org/10.1038/s41467-018-08282-8

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