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Circulating GATA2 mRNA is decreased among women destined to develop preeclampsia and may be of endothelial origin
Preeclampsia is a pregnancy complication associated with elevated placental secretion of anti-angiogenic factors, maternal endothelial dysfunction and organ injury. GATA2 is a transcription factor expressed in the endothelium which regulates vascular homeostasis by controlling transcription of genes...
Autores principales: | Whigham, Carole-Anne, MacDonald, Teresa M., Walker, Susan P., Pritchard, Natasha, Hannan, Natalie J., Cannon, Ping, Nguyen, Tuong Vi, Hastie, Roxanne, Tong, Stephen, Kaitu’u-Lino, Tu’uhevaha J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338784/ https://www.ncbi.nlm.nih.gov/pubmed/30659233 http://dx.doi.org/10.1038/s41598-018-36645-0 |
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