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E47 modulates hepatic glucocorticoid action

Glucocorticoids (GCs) are effective drugs, but their clinical use is compromised by severe side effects including hyperglycemia, hyperlipidemia and obesity. They bind to the Glucocorticoid Receptor (GR), which acts as a transcription factor. The activation of metabolic genes by GR is thought to unde...

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Detalles Bibliográficos
Autores principales: Hemmer, M. Charlotte, Wierer, Michael, Schachtrup, Kristina, Downes, Michael, Hübner, Norbert, Evans, Ronald M., Uhlenhaut, N. Henriette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338785/
https://www.ncbi.nlm.nih.gov/pubmed/30659202
http://dx.doi.org/10.1038/s41467-018-08196-5