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E47 modulates hepatic glucocorticoid action
Glucocorticoids (GCs) are effective drugs, but their clinical use is compromised by severe side effects including hyperglycemia, hyperlipidemia and obesity. They bind to the Glucocorticoid Receptor (GR), which acts as a transcription factor. The activation of metabolic genes by GR is thought to unde...
Autores principales: | Hemmer, M. Charlotte, Wierer, Michael, Schachtrup, Kristina, Downes, Michael, Hübner, Norbert, Evans, Ronald M., Uhlenhaut, N. Henriette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338785/ https://www.ncbi.nlm.nih.gov/pubmed/30659202 http://dx.doi.org/10.1038/s41467-018-08196-5 |
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