Malonylation of GAPDH is an inflammatory signal in macrophages

Macrophages undergo metabolic changes during activation that are coupled to functional responses. The gram negative bacterial product lipopolysaccharide (LPS) is especially potent at driving metabolic reprogramming, enhancing glycolysis and altering the Krebs cycle. Here we describe a role for the c...

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Detalles Bibliográficos
Autores principales: Galván-Peña, Silvia, Carroll, Richard G., Newman, Carla, Hinchy, Elizabeth C., Palsson-McDermott, Eva, Robinson, Elektra K., Covarrubias, Sergio, Nadin, Alan, James, Andrew M., Haneklaus, Moritz, Carpenter, Susan, Kelly, Vincent P., Murphy, Michael P., Modis, Louise K., O’Neill, Luke A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338787/
https://www.ncbi.nlm.nih.gov/pubmed/30659183
http://dx.doi.org/10.1038/s41467-018-08187-6

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