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An evolutionarily-conserved Wnt3/β-catenin/Sp5 feedback loop restricts head organizer activity in Hydra

Polyps of the cnidarian Hydra maintain their adult anatomy through two developmental organizers, the head organizer located apically and the foot organizer basally. The head organizer is made of two antagonistic cross-reacting components, an activator, driving apical differentiation and an inhibitor...

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Detalles Bibliográficos
Autores principales: Vogg, Matthias C., Beccari, Leonardo, Iglesias Ollé, Laura, Rampon, Christine, Vriz, Sophie, Perruchoud, Chrystelle, Wenger, Yvan, Galliot, Brigitte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338789/
https://www.ncbi.nlm.nih.gov/pubmed/30659200
http://dx.doi.org/10.1038/s41467-018-08242-2