Hematopoietic PBX-interacting protein mediates cartilage degeneration during the pathogenesis of osteoarthritis

Osteoarthritis (OA) has been recognized as the most common chronic age-related disease. Cartilage degeneration influences OA therapy. Here we report that hematopoietic pre-B cell leukemia transcription factor-interacting protein (HPIP) is essential for OA development. Elevated HPIP levels are found...

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Detalles Bibliográficos
Autores principales: Ji, Quanbo, Xu, Xiaojie, Kang, Lei, Xu, Yameng, Xiao, Jingbo, Goodman, Stuart B., Zhu, Xiang, Li, Wenchao, Liu, Juan, Gao, Xu, Yan, Zhifeng, Zheng, Yuxuan, Wang, Zheng, Maloney, William J., Ye, Qinong, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338798/
https://www.ncbi.nlm.nih.gov/pubmed/30659184
http://dx.doi.org/10.1038/s41467-018-08277-5

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