Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma

Glioblastoma multiforme (GBM) is a highly aggressive malignant brain tumor with fatal outcome. Tumor-associated macrophages and microglia (TAMs) have been found to be major tumor-promoting immune cells in the tumor microenvironment. Hence, modulation and reeducation of tumor-associated macrophages a...

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Detalles Bibliográficos
Autores principales: Hutter, Gregor, Theruvath, Johanna, Graef, Claus Moritz, Zhang, Michael, Schoen, Matthew Kenneth, Manz, Eva Maria, Bennett, Mariko L., Olson, Andrew, Azad, Tej D., Sinha, Rahul, Chan, Carmel, Assad Kahn, Suzana, Gholamin, Sharareh, Wilson, Christy, Grant, Gerald, He, Joy, Weissman, Irving L., Mitra, Siddhartha S., Cheshier, Samuel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338872/
https://www.ncbi.nlm.nih.gov/pubmed/30602457
http://dx.doi.org/10.1073/pnas.1721434116

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