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Combined Influence of Depression and Physical Frailty on Cognitive Impairment in Patients with Heart Failure

Cognitive impairment is a prevalent condition and important barrier to self-care behaviors in patients with heart failure (HF). HF patients with depression or physical frailty are more likely to have reduced cognitive function. However, it remains unclear if combined depression and physical frailty...

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Autores principales: Lee, Jong Kyung, Won, Mi Hwa, Son, Youn-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338900/
https://www.ncbi.nlm.nih.gov/pubmed/30591673
http://dx.doi.org/10.3390/ijerph16010066
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author Lee, Jong Kyung
Won, Mi Hwa
Son, Youn-Jung
author_facet Lee, Jong Kyung
Won, Mi Hwa
Son, Youn-Jung
author_sort Lee, Jong Kyung
collection PubMed
description Cognitive impairment is a prevalent condition and important barrier to self-care behaviors in patients with heart failure (HF). HF patients with depression or physical frailty are more likely to have reduced cognitive function. However, it remains unclear if combined depression and physical frailty increased the risk of cognitive impairments among HF populations. This study aimed to identify the influence of combined depression and physical frailty on cognitive impairments in HF. This cross-sectional study was included 289 patients with HF in outpatient cardiology clinics at a tertiary care university hospital in Cheonan, South Korea. We obtained patients’ characteristics including depression, physical frailty, and cognitive function with Korean validated tools using a face-to-face interview. The prevalence rate of cognitive impairment was approximately 27.3% in HF outpatients. We found that the combined influence of depression and physical frailty increased the risk of cognitive impairments in both unadjusted (odds ratio (OR) 4.360; 95% confidence interval (CI) (2.113, 8.994)) and adjusted models (OR 3.545; 95% CI (1.448, 8.681)). Our findings highlight that healthcare professionals need to be more aware of the vulnerable population who suffer from both depression and physical frailty at the same time. Future prospective studies should examine the causal relationships among depression, physical frailty and cognitive impairment during the HF illness trajectories.
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spelling pubmed-63389002019-01-23 Combined Influence of Depression and Physical Frailty on Cognitive Impairment in Patients with Heart Failure Lee, Jong Kyung Won, Mi Hwa Son, Youn-Jung Int J Environ Res Public Health Article Cognitive impairment is a prevalent condition and important barrier to self-care behaviors in patients with heart failure (HF). HF patients with depression or physical frailty are more likely to have reduced cognitive function. However, it remains unclear if combined depression and physical frailty increased the risk of cognitive impairments among HF populations. This study aimed to identify the influence of combined depression and physical frailty on cognitive impairments in HF. This cross-sectional study was included 289 patients with HF in outpatient cardiology clinics at a tertiary care university hospital in Cheonan, South Korea. We obtained patients’ characteristics including depression, physical frailty, and cognitive function with Korean validated tools using a face-to-face interview. The prevalence rate of cognitive impairment was approximately 27.3% in HF outpatients. We found that the combined influence of depression and physical frailty increased the risk of cognitive impairments in both unadjusted (odds ratio (OR) 4.360; 95% confidence interval (CI) (2.113, 8.994)) and adjusted models (OR 3.545; 95% CI (1.448, 8.681)). Our findings highlight that healthcare professionals need to be more aware of the vulnerable population who suffer from both depression and physical frailty at the same time. Future prospective studies should examine the causal relationships among depression, physical frailty and cognitive impairment during the HF illness trajectories. MDPI 2018-12-27 2019-01 /pmc/articles/PMC6338900/ /pubmed/30591673 http://dx.doi.org/10.3390/ijerph16010066 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lee, Jong Kyung
Won, Mi Hwa
Son, Youn-Jung
Combined Influence of Depression and Physical Frailty on Cognitive Impairment in Patients with Heart Failure
title Combined Influence of Depression and Physical Frailty on Cognitive Impairment in Patients with Heart Failure
title_full Combined Influence of Depression and Physical Frailty on Cognitive Impairment in Patients with Heart Failure
title_fullStr Combined Influence of Depression and Physical Frailty on Cognitive Impairment in Patients with Heart Failure
title_full_unstemmed Combined Influence of Depression and Physical Frailty on Cognitive Impairment in Patients with Heart Failure
title_short Combined Influence of Depression and Physical Frailty on Cognitive Impairment in Patients with Heart Failure
title_sort combined influence of depression and physical frailty on cognitive impairment in patients with heart failure
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338900/
https://www.ncbi.nlm.nih.gov/pubmed/30591673
http://dx.doi.org/10.3390/ijerph16010066
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