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Damping Force and Loading Position Dependence of Mass Sensitivity of Magnetoelastic Biosensors in Viscous Liquid
We established the vibration governing equation for a magnetoelastic (ME) biosensor with target loading in liquid. Based on the equation, a numerical simulation approach was used to determine the effect of the target loading position and viscous damping coefficient on the node (“blind points”) and m...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339079/ https://www.ncbi.nlm.nih.gov/pubmed/30585200 http://dx.doi.org/10.3390/s19010067 |
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author | Zhang, Kewei Chen, Zhe Zhu, Qianke Jiang, Yong Liu, Wenfeng Wu, Peixuan |
author_facet | Zhang, Kewei Chen, Zhe Zhu, Qianke Jiang, Yong Liu, Wenfeng Wu, Peixuan |
author_sort | Zhang, Kewei |
collection | PubMed |
description | We established the vibration governing equation for a magnetoelastic (ME) biosensor with target loading in liquid. Based on the equation, a numerical simulation approach was used to determine the effect of the target loading position and viscous damping coefficient on the node (“blind points”) and mass sensitivity (S(m)) of an ME biosensor under different order resonances. The results indicate that viscous damping force causes the specific nodes shift but does not affect the overall variation trend of S(m) as the change of target loading position and the effect on Sm gradually reduces when the target approaches to the node. In addition, S(m) decreases with the increase of viscous damping coefficient but the tendency becomes weak at high-order resonance. Moreover, the effect of target loading position on S(m) decreases with the increase of viscous damping coefficient. Finally, the results provide certain guidance on improving the mass sensitivity of an ME biosensor in liquid by controlling the target loading position. |
format | Online Article Text |
id | pubmed-6339079 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-63390792019-01-23 Damping Force and Loading Position Dependence of Mass Sensitivity of Magnetoelastic Biosensors in Viscous Liquid Zhang, Kewei Chen, Zhe Zhu, Qianke Jiang, Yong Liu, Wenfeng Wu, Peixuan Sensors (Basel) Article We established the vibration governing equation for a magnetoelastic (ME) biosensor with target loading in liquid. Based on the equation, a numerical simulation approach was used to determine the effect of the target loading position and viscous damping coefficient on the node (“blind points”) and mass sensitivity (S(m)) of an ME biosensor under different order resonances. The results indicate that viscous damping force causes the specific nodes shift but does not affect the overall variation trend of S(m) as the change of target loading position and the effect on Sm gradually reduces when the target approaches to the node. In addition, S(m) decreases with the increase of viscous damping coefficient but the tendency becomes weak at high-order resonance. Moreover, the effect of target loading position on S(m) decreases with the increase of viscous damping coefficient. Finally, the results provide certain guidance on improving the mass sensitivity of an ME biosensor in liquid by controlling the target loading position. MDPI 2018-12-25 /pmc/articles/PMC6339079/ /pubmed/30585200 http://dx.doi.org/10.3390/s19010067 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zhang, Kewei Chen, Zhe Zhu, Qianke Jiang, Yong Liu, Wenfeng Wu, Peixuan Damping Force and Loading Position Dependence of Mass Sensitivity of Magnetoelastic Biosensors in Viscous Liquid |
title | Damping Force and Loading Position Dependence of Mass Sensitivity of Magnetoelastic Biosensors in Viscous Liquid |
title_full | Damping Force and Loading Position Dependence of Mass Sensitivity of Magnetoelastic Biosensors in Viscous Liquid |
title_fullStr | Damping Force and Loading Position Dependence of Mass Sensitivity of Magnetoelastic Biosensors in Viscous Liquid |
title_full_unstemmed | Damping Force and Loading Position Dependence of Mass Sensitivity of Magnetoelastic Biosensors in Viscous Liquid |
title_short | Damping Force and Loading Position Dependence of Mass Sensitivity of Magnetoelastic Biosensors in Viscous Liquid |
title_sort | damping force and loading position dependence of mass sensitivity of magnetoelastic biosensors in viscous liquid |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339079/ https://www.ncbi.nlm.nih.gov/pubmed/30585200 http://dx.doi.org/10.3390/s19010067 |
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