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PIXER: an automated particle-selection method based on segmentation using a deep neural network
BACKGROUND: Cryo-electron microscopy (cryo-EM) has become a widely used tool for determining the structures of proteins and macromolecular complexes. To acquire the input for single-particle cryo-EM reconstruction, researchers must select hundreds of thousands of particles from micrographs. As the s...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339297/ https://www.ncbi.nlm.nih.gov/pubmed/30658571 http://dx.doi.org/10.1186/s12859-019-2614-y |