Three-dimensional nanostructured substrates enable dynamic detection of ALK-rearrangement in circulating tumor cells from treatment-naive patients with stage III/IV lung adenocarcinoma

BACKGROUND: Circulating tumor cells (CTC) shows great prospect to realize precision medicine in cancer patients. METHODS: We developed the NanoVelcro Chip integrating three functional mechanisms. NanoVelcro CTC capture efficiency was tested in stage III or IV lung adenocarcinoma. Further, ALK-rearra...

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Detalles Bibliográficos
Autores principales: He, Weiling, Xu, Di, Wang, Zhuo, Wu, Hui, Xiang, Xianhong, Tang, Bing, Jiang, Wenting, Cui, Yongmei, Wang, Han, Jiang, Neng, Sun, Yu, Chen, Yangshan, Li, Shuhua, Hou, Minzhi, Zhang, Yang, Wang, Liantang, Ke, Zun-fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339314/
https://www.ncbi.nlm.nih.gov/pubmed/30658713
http://dx.doi.org/10.1186/s12967-019-1779-5

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