Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations

Parkinson’s disease (PD) is associated with both motor and non-motor symptoms, including constipation, sensory neuropathy, depression, dementia and sleep disorder. Somatostatin (SST) is considered to be a modulator of GABAergic inhibitory transmission, and its levels are reduced in cerebrospinal flu...

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Detalles Bibliográficos
Autores principales: Iwasawa, Chizuru, Kuzumaki, Naoko, Suda, Yukari, Kagawa, Reiko, Oka, Yuko, Hattori, Nobutaka, Okano, Hideyuki, Narita, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339354/
https://www.ncbi.nlm.nih.gov/pubmed/30658665
http://dx.doi.org/10.1186/s13041-019-0426-7

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