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All-trans retinoic acid stimulates the secretion of TGF-β2 via the phospholipase C but not the adenylyl cyclase signaling pathway in retinal pigment epithelium cells

BACKGROUND: By investigating that (i) all-trans retinoic acid (ATRA) affects human retinal pigment epithelium (RPE) in expressing and secreting transforming growth factor (TGF)-β(2) and (ii) U73122 (phospholipase C inhibitor) and SQ22536 (adenylyl cyclase inhibitor) regulate the ATRA-induced secreti...

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Detalles Bibliográficos
Autores principales:	Zhang, Daren, Deng, Zhihong, Tan, Jia, Liu, Shuirong, Hu, Shuyu, Tao, Hui, Tang, Renhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339369/ https://www.ncbi.nlm.nih.gov/pubmed/30658598 http://dx.doi.org/10.1186/s12886-018-1017-6

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