Implementation of massive sequencing in the genetic diagnosis of hereditary cancer syndromes: diagnostic performance in the Hereditary Cancer Programme of the Valencia Community (FamCan-NGS)

BACKGROUND: Approximately 5 to 10% of all cancers are caused by inherited germline mutations, many of which are associated with different Hereditary Cancer Syndromes (HCS). In the context of the Program of Hereditary Cancer of the Valencia Community, individuals belonging to specific HCS and their f...

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Detalles Bibliográficos
Autores principales: Ramírez-Calvo, Marta, García-Casado, Zaida, Fernández-Serra, Antonio, de Juan, Inmaculada, Palanca, Sarai, Oltra, Silvestre, Soto, José Luis, Castillejo, Adela, Barbera, Víctor M, Juan-Fita, Ma José, Segura, Ángel, Chirivella, Isabel, Sánchez, Ana Beatriz, Tena, Isabel, Chaparro, Carolina, Salas, Dolores, López-Guerrero, José Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339395/
https://www.ncbi.nlm.nih.gov/pubmed/30675318
http://dx.doi.org/10.1186/s13053-019-0104-x

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