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Tbet-positive regulatory T cells accumulate in oropharyngeal cancers with ongoing tumor-specific type 1 T cell responses

Regulatory T cells (Tregs) may comprise different subsets allowing them to efficiently suppress different types of effector T cells. In this study, we show that high numbers of both conventional and Tbet co-expressing Foxp3(hi) Tregs accumulate in human papilloma virus (HPV)-driven oropharyngeal squ...

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Detalles Bibliográficos
Autores principales:	Santegoets, S. J., Duurland, C. L., Jordanova, E. S., van Ham, J. J., Ehsan, I., van Egmond, S. L., Welters, M. J. P., van der Burg, S. H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339415/ https://www.ncbi.nlm.nih.gov/pubmed/30658697 http://dx.doi.org/10.1186/s40425-019-0497-0

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