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Vascular endothelial cadherin shedding is more severe in sepsis patients with severe acute kidney injury

BACKGROUND: Vascular endothelial cadherin (VE-cadherin) is a membrane protein that is the major component of adherens junctions between endothelial cells. It is crucial for regulating vascular integrity, endothelial permeability, and angiogenesis. During inflammatory processes, VE-cadherin is shed i...

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Detalles Bibliográficos
Autores principales: Yu, Wen-Kuang, McNeil, J. Brennan, Wickersham, Nancy E., Shaver, Ciara M., Bastarache, Julie A., Ware, Lorraine B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339439/
https://www.ncbi.nlm.nih.gov/pubmed/30658667
http://dx.doi.org/10.1186/s13054-019-2315-y