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Reflexive Laboratory-Based Cryptococcal Antigen Screening and Preemptive Fluconazole Therapy for Cryptococcal Antigenemia in HIV-Infected Individuals With CD4 <100 Cells/µL: A Stepped-Wedge, Cluster-Randomized Trial

BACKGROUND: HIV-infected persons with cryptococcal antigenemia (CrAg) are at high risk for meningitis or death. We evaluated the effect of CrAg screening and preemptive fluconazole therapy, adjunctive to antiretroviral therapy (ART), on 6-month survival among persons with advanced HIV/AIDS. METHODS:...

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Detalles Bibliográficos
Autores principales:	Meya, David B., Kiragga, Agnes N., Nalintya, Elizabeth, Morawski, Bozena M., Rajasingham, Radha, Park, Benjamin J., Mubiru, Anthony, Kaplan, Jonathan E., Manabe, Yukari C., Boulware, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JAIDS Journal of Acquired Immune Deficiency Syndromes 2019
Materias:	Clinical Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339522/ https://www.ncbi.nlm.nih.gov/pubmed/30399034 http://dx.doi.org/10.1097/QAI.0000000000001894

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