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SWI/SNF remains localized to chromatin in the presence of SCHLAP1

SCHLAP1 is a long-noncoding RNA that is reported to function by depleting the SWI/SNF complex from the genome. We investigated the hypothesis that SCHLAP1 affects only specific compositions of SWI/SNF. Using several assays we found that SWI/SNF is not depleted from the genome by SCHLAP1, and that SW...

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Detalles Bibliográficos
Autores principales: Raab, Jesse R., Smith, Keriayn N., Spear, Camarie C., Manner, Carl J., Calabrese, J. Mauro, Magnuson, Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339527/
https://www.ncbi.nlm.nih.gov/pubmed/30510238
http://dx.doi.org/10.1038/s41588-018-0272-z