The Janus face of HMGB1 in heart disease: a necessary update

High mobility group box 1 (HMGB1) is a ubiquitous nuclear protein involved in transcription regulation, DNA replication and repair and nucleosome assembly. HMGB1 is passively released by necrotic tissues or actively secreted by stressed cells. Extracellular HMGB1 acts as a damage-associated molecula...

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Detalles Bibliográficos
Autores principales: Raucci, Angela, Di Maggio, Stefania, Scavello, Francesco, D’Ambrosio, Alessandro, Bianchi, Marco E., Capogrossi, Maurizio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339675/
https://www.ncbi.nlm.nih.gov/pubmed/30306212
http://dx.doi.org/10.1007/s00018-018-2930-9

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