Loss of the interaction between estradiol and insulin-like growth factor I in brain endothelial cells associates to changes in mood homeostasis during peri-menopause in mice

We recently reported that exercise increases resilience to stress in young female mice. Underlying mechanisms include an interaction of the ovarian hormone estradiol (E2) with insulin-like growth factor I (IGF-I), and an increase in the hippocampal levels of the latter. Since changes in mood regulat...

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Detalles Bibliográficos
Autores principales: Munive, Victor, Zegarra-Valdivia, Jonathan A., Herrero-Labrador, Raquel, Fernandez, Ana M., Aleman, Ignacio Torres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339786/
https://www.ncbi.nlm.nih.gov/pubmed/30636168
http://dx.doi.org/10.18632/aging.101739

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