Mitochondrial distribution violation and nuclear indentations in neurons differentiated from iPSCs of Huntington’s disease patients

AIM: Huntington’s disease (HD) is an inherited disease caused by an expansion of cytosine-adenine-guanine (CAG) repeats in the huntingtin gene (HTT) that ultimately leads to neurodegeneration. To study the molecular basis of this disease, induced pluripotent stem cells (iPSCs) generated from patient...

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Detalles Bibliográficos
Autores principales: Nekrasov, Evgeny D, Kiselev, Sergey L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Stem Cells and Regenerative Medicine 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339978/
https://www.ncbi.nlm.nih.gov/pubmed/30679892

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