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Chikungunya Virus Fidelity Variants Exhibit Differential Attenuation and Population Diversity in Cell Culture and Adult Mice

Chikungunya virus (CHIKV) is a reemerging global health threat that produces debilitating arthritis in people. Like other RNA viruses with high mutation rates, CHIKV produces populations of genetically diverse genomes within a host. While several known CHIKV mutations influence disease severity in v...

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Detalles Bibliográficos
Autores principales:	Riemersma, Kasen K., Steiner, Cody, Singapuri, Anil, Coffey, Lark L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Genetic Diversity and Evolution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340026/ https://www.ncbi.nlm.nih.gov/pubmed/30429348 http://dx.doi.org/10.1128/JVI.01606-18

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