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Molecular and in vivo Functions of the CDK8 and CDK19 Kinase Modules
CDK8 and its paralog, CDK19, collectively termed ‘Mediator Kinase,’ are cyclin-dependent kinases that have been implicated as key rheostats in cellular homeostasis and developmental programming. CDK8 and CDK19 are incorporated, in a mutually exclusive manner, as part of a 4-protein complex called th...
Autores principales: | Dannappel, Marius Volker, Sooraj, Dhanya, Loh, Jia Jian, Firestein, Ron |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340071/ https://www.ncbi.nlm.nih.gov/pubmed/30693281 http://dx.doi.org/10.3389/fcell.2018.00171 |
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