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Implementing Central Composite Design for Developing Transdermal Diacerein-Loaded Niosomes: Ex vivo Permeation and In vivo Deposition

BACKGROUND: Niosomes are surfactant-based vesicular nanosystems that proved their efficien-cy in transdermal delivery by overcoming skin inherent anatomic barrier; startum corneum. Central com-posite design is an efficient tool for developing and optimizing niosomal formulations using fewer exper-im...

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Detalles Bibliográficos
Autores principales:	Aziz, Diana Edwar, Abdelbary, Aly Ahmed, Elassasy, Abdelhalim Ibrahim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340157/ https://www.ncbi.nlm.nih.gov/pubmed/29921206 http://dx.doi.org/10.2174/1567201815666180619105419

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