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Endoplasmic Reticulum Stress Response of Trabecular Meshwork Stem Cells and Trabecular Meshwork Cells and Protective Effects of Activated PERK Pathway
PURPOSE: This study aimed to investigate the differential responses of trabecular meshwork stem cells (TMSCs) and trabecular meshwork (TM) cells to endoplasmic reticulum (ER) stress inducers. METHODS: Human TM cells and TMSCs were exposed to tunicamycin, brefeldin A, or thapsigargin. Cell apoptosis...
Autores principales: | Wang, Yiwen, Osakue, Deborah, Yang, Enzhi, Zhou, Yi, Gong, Haiyan, Xia, Xiaobo, Du, Yiqin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340162/ https://www.ncbi.nlm.nih.gov/pubmed/30654386 http://dx.doi.org/10.1167/iovs.18-25477 |
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