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Endoplasmic Reticulum Stress Response of Trabecular Meshwork Stem Cells and Trabecular Meshwork Cells and Protective Effects of Activated PERK Pathway

PURPOSE: This study aimed to investigate the differential responses of trabecular meshwork stem cells (TMSCs) and trabecular meshwork (TM) cells to endoplasmic reticulum (ER) stress inducers. METHODS: Human TM cells and TMSCs were exposed to tunicamycin, brefeldin A, or thapsigargin. Cell apoptosis...

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Detalles Bibliográficos
Autores principales:	Wang, Yiwen, Osakue, Deborah, Yang, Enzhi, Zhou, Yi, Gong, Haiyan, Xia, Xiaobo, Du, Yiqin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2019
Materias:	Glaucoma
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340162/ https://www.ncbi.nlm.nih.gov/pubmed/30654386 http://dx.doi.org/10.1167/iovs.18-25477

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