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Low Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria
Vaccines that target Plasmodium falciparum gametocytes have the potential to reduce malaria transmission and are thus attractive targets for malaria control. However, very little is known about human immune responses to gametocytes present in human hosts. We evaluated naturally-acquired antibodies t...
Autores principales: | Chan, Jo-Anne, Drew, Damien R., Reiling, Linda, Lisboa-Pinto, Ashley, Dinko, Bismarck, Sutherland, Colin J., Dent, Arlene E., Chelimo, Kiprotich, Kazura, James W., Boyle, Michelle J., Beeson, James G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340286/ https://www.ncbi.nlm.nih.gov/pubmed/30692996 http://dx.doi.org/10.3389/fimmu.2018.03126 |
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