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Crystal structure of the natural anion-conducting channelrhodopsin GtACR1
The naturally occurring channelrhodopsin variant anion channelrhodopsin-1 (ACR1), discovered in the cryptophyte algae Guillardia theta, exhibits large light-gated anion conductance and high anion selectivity when expressed in heterologous settings, properties that support its use as an optogenetic t...
Autores principales: | Kim, Yoon Seok, Kato, Hideaki E., Yamashita, Keitaro, Ito, Shota, Inoue, Keiichi, Ramakrishnan, Charu, Fenno, Lief E., Evans, Kathryn E., Paggi, Joseph M., Dror, Ron O., Kandori, Hideki, Kobilka, Brian K., Deisseroth, Karl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340299/ https://www.ncbi.nlm.nih.gov/pubmed/30158696 http://dx.doi.org/10.1038/s41586-018-0511-6 |
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